Inhibition of Candida albicans biofilm by synergistic action of exogenous terpenoides
نویسندگان
چکیده
منابع مشابه
Candida albicans biofilm inhibition by synergistic action of terpenes and fluconazole.
The current treatment options for Candida albicans biofilm-device related infections are very scarce due to their intrinsic increased tolerance to antimycotics. The aim of this work was to study synergistic action of terpenes (eugenol, menthol and thymol) with fluconazole (FLA) on C. albicans biofilm inhibition. The minimum inhibitory concentration (MIC) assayed using CLSI M27-A3 broth micro-di...
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A biofilm is a surface-associated population of microorganisms embedded in a matrix of extracellular polymeric substances. Biofilms are a major natural growth form of microorganisms and the cause of pervasive device-associated infection. This report focuses on the biofilm matrix of Candida albicans, the major fungal pathogen of humans. We report here that the C. albicans zinc-response transcrip...
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A radio assay employing 14C-uridine to measure the intracellular killing of Candida albicans by phagocytes is presented. The principle of this new method is that after killing of Candida albicans by phagocytes RNA synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high CPM counts can be obtained within 135 min...
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ژورنال
عنوان ژورنال: Journal of Infection and Public Health
سال: 2019
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2018.10.059